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Nelson Syndrome

Synonyms

• Pituitary Tumor after Adrenalectomy
• Bilateral adrenalectomy
• Cushing’s disease
• Cushing’s disease adrenocorticotropin
• ACTH-secreting pituitary adenoma

Disorder Subdivisions

• None

General Discussion

Nelson syndrome is a disorder characterized by abnormal hormone secretion, enlargement of the pituitary gland (hypophysis), and the development of large and invasive growths known as adenomas. It occurs in an estimated 15 to 25 percent of people who undergo surgical removal of the adrenal glands for Cushing disease. Symptoms associated with Nelson syndrome include intense skin discoloration (hyperpigmentation), headaches, vision impairment, and the cessation of menstrual periods in women.

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