can you tell me about gallstone ?

A small, hard, pathological concretion, composed chiefly of cholesterol, Calcium salts, and bile pigments, formed in the gallbladder or in a bile duct.

Gallstones are common--they occur in approximately 20% of Women in the US, Canada and Europe--but there is a large variation in prevalence among ethnic groups. For example, gallstones occur 1 ? to 2 times more commonly among Scandinavians and Mexican-Americans. Among American Indians, gallstone prevalence reaches more than 80%. These differences probably are accounted for by genetic (hereditary) factors. First-degree relatives (parents, siblings, and Children) of individuals with gallstones are 1 ? times more likely to have gallstones than if there were not a first-degree relative with gallstones. Further support that genetic factors are important in determining who gets gallstones comes from twin studies. Among non-identical pairs of twins (who share 50% of their genes with each other), both individuals in a pair have gallstones 8% of the time. Among identical pairs of twins (who share 100% of their genes with each other), both individuals in a pair have gallstones 23% of the time.

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